Renin: Purification, structure determination and active site.
نویسندگان
چکیده
منابع مشابه
Purification of acetylcholinesterase by affinity chromatography and determination of active site stoichiometry.
Specific inhibitors of acetylcholinesterase have been prepared and attached to Sepharose. When crude preparations of the enzyme are chromatographed on the aflinity gel, the enzyme is selectively retained and may be eluted by a salt gradient. Conditions have been defined under which enzyme is purified some ZO-fold in one step to a homogeneous and apparently pure species. An essential factor appe...
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In this issue of the journal, we feature two articles—one by Tadashi Inagami and the other by Pierre Corvol and Joel Menard—relating the story of the purification of renin. These investigators received the 1985 CIBA Award for Hypertension Research for biochemical studies leading to the isolation, amino acid structural and three-dimensional configuration, and the physiochemical and immunochemica...
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ژورنال
عنوان ژورنال: Proceedings of the Japan Academy, Series B
سال: 1986
ISSN: 0386-2208,1349-2896
DOI: 10.2183/pjab.62.197